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Image Search Results
Journal: Animals : an Open Access Journal from MDPI
Article Title: Whole-Genome Identification and Characterization of the DKK Gene Family and Its Transcription Profiles: An Analysis of the Chinese Soft-Shell Turtle ( Pelodiscus sinensis )
doi: 10.3390/ani14060931
Figure Lengend Snippet: DKK protein analysis of P. sinensis .
Article Snippet: All genome sequences, protein sequences, and annotation files of
Techniques: Molecular Weight
Journal: bioRxiv
Article Title: A SNAI2-PEAK1 stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting a cytokine expression profile that converges on PI3K/Akt signaling
doi: 10.1101/2020.05.15.098772
Figure Lengend Snippet: a. Kaplan-Meier relapse-free survival (RFS) curves for patients with low or high PEAK1 transcript levels across all breast cancer subtypes (n = 1784). b. Kaplan-Meier RFS curves for HER2-positive breast cancer patients with low or high PEAK1 transcript levels (n = 272). c. PEAK1 transcript levels in normal breast stroma and breast cancer stroma across all subtypes (n = 6 and 53, respectively). d. PEAK1 transcript levels in breast cancer stroma of relapse-free patients and those with disease recurrence across all subtypes (n = 42 and 11, respectively). e. Expression correlation and linear regression analyses of PEAK1 and ETS1, KLF4, SNAI2, FN1, FOXC2 and MYC across patients having mixed or good outcomes (top, n = 45) and patients having poor outcomes (bottom, n = 8). f. Representative IHC images for HER2, PEAK1, SNAI2, MYC and FN1 in breast cancer tissue where PEAK1 expression in the stromal compartment is low (top) or high (bottom). g. Stromal IHC score correlation and linear regression analyses of PEAK1 and SNAI2, MYC and FN1 across six breast cancer tissue samples (patient #s 1874, 1939, 2428, 1920, 2392 and 3257). h. Average stromal IHC scores for PEAK1, SNAI2, MYC and FN1 in three HER2-negative patients and three HER2-positive patients. i-j. Kaplan-Meier overall survival (OS) curves for patients with low or high PEAK1 (h) or SNAI2 (i) transcript levels across all breast cancer subtypes (n = 1089). k-l. Kaplan-Meier OS curves for low or high PEAK1 transcript levels in breast cancer patients selected for low (j) or high (k) SNAI2 expression (n = 544). m. Kaplan-Meier RFS curves for low or high PEAK1 transcript levels in HER2-positive breast cancer patient selected for high SNAI2 expression (n = 75). * or ** indicates p-value < 0.05 or 0.01, respectively, as determined by a Student’s T-test.
Article Snippet:
Techniques: Expressing